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Protein structural similarity database: the architecture and implementation

Tomo Česnik (2011) Protein structural similarity database: the architecture and implementation. EngD thesis.

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    Abstract

    The work described in this thesis builds upon ProBiS algorithm for comparison of protein structures. Such comparisons can be very time consuming. The main goal of our project was their pre computation and development of the ProBiS database. Thesis begins with a description of ProBiS algorithm and a web page, through which it operates. Our main contribution is construction of appropriate architecture of the system and its implementation using distributed computation, and construction of a database and its further optimization through denormalization. We have also implemented the user interface for searching the database. Our newly developed ProBiS database is a novel resource for protein structural comparisons and greatly improves the user experience of ProBiS web server.

    Item Type: Thesis (EngD thesis)
    Keywords: ProBiS, protein, database, distributed computation, denormalization, user interface
    Number of Pages: 39
    Language of Content: Slovenian
    Mentor / Comentors:
    Name and SurnameIDFunction
    prof. dr. Blaž Zupan106Mentor
    doc. dr. Janez KoncComentor
    Link to COBISS: http://www.cobiss.si/scripts/cobiss?command=search&base=50070&select=(ID=00008691028)
    Institution: University of Ljubljana
    Department: Faculty of Computer and Information Science
    Item ID: 1548
    Date Deposited: 28 Sep 2011 15:24
    Last Modified: 12 Oct 2011 22:03
    URI: http://eprints.fri.uni-lj.si/id/eprint/1548

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