Miha Svalina (2013) Development of a DNA microarray data repository. EngD thesis.
Abstract
Researchers at National Institute of Biology (NIB) use DNA microarray technology in their experimental work. Experimental data is currently saved in the form of files and just about every researcher at the Institute uses its own file format. To support searching through all experimental data by everyone at NIB, there was a need to develop a centralised application for DNA microarray data management. We have addressed this task by developing an application called Fitobase. The application allows user to describe the parameters of the experiment, upload the data, and search through the data sets stored in Fitobase. It also provides graphical visualisation of gene expression, supporting a simple means of data analysis. With analysis and comparison of gene expressions across different biological contexts, Fitobase can help biologists to understand the behaviour of the model organisms at different conditions and to hypothesise on gene function.
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