Qualitative analysis of biological oscillators as processing structures

Jure Bordon (2011) Qualitative analysis of biological oscillators as processing structures. EngD thesis.

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Abstract

Recently there is a certain tendency in the field of computer science to find alternative processing platforms, which would replace the conventional ones that are starting to reach their limits in the meaning of components' size and speed. Computer science is trying to avoid its dependency on traditional electronic components. One of such alternatives is also processing in biological systems. Whatever the future processing platform might be, computer science will most likely always need a component which would synchronize the processing elements. One of the basic elements for synchronization is an oscillator. Oscillator, i.e. repressilator, was already realized as a biological system using gene regulatory networks. Different deterministic models describing a repressilator will be presented in this work. They will be used in order to qualitatively analyze repressilators with different numbers of repressors and different binding cooperativity. Using the results of this analysis different models as well as different sizes of repressilators for each model will be compared among each other.

Item Type:

Thesis (EngD thesis)

Keywords:

modeling, deterministic modeling, biological oscillator, repressilator, stability analysis, bifurcation analysis, bifurcation, gene regulatory network, ordinary differential equations

Number of Pages:

Language of Content:

Slovenian

Mentor / Comentors:

Name and Surname	ID	Function
izr. prof. dr. Miha Mraz	249	Mentor

Link to COBISS:

http://www.cobiss.si/scripts/cobiss?command=search&base=50070&select=(ID=00008552276)

Institution:

University of Ljubljana

Department:

Faculty of Computer and Information Science

Item ID:

1487

Date Deposited:

17 Aug 2011 15:29

Last Modified:

29 Aug 2011 13:59

URI:

http://eprints.fri.uni-lj.si/id/eprint/1487

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